Manufacture of basic pharmaceutical products

NACE v2.0 Code: C21.10

About manufacture of basic pharmaceutical products

NACE code 21.10 covers the manufacture of basic pharmaceutical products, a critical industry that plays a vital role in the global healthcare system. This industry is responsible for the production of the active ingredients and formulations that form the foundation of modern medicine, enabling the development and distribution of essential drugs, vaccines, and other pharmaceutical products. As a highly regulated and research-intensive sector, the manufacture of basic pharmaceutical products is a key driver of innovation and economic growth, with significant impacts across the broader economy.

Production process

The manufacture of basic pharmaceutical products involves a complex set of production techniques and processes. This typically begins with the extraction, synthesis, or fermentation of active pharmaceutical ingredients (APIs) from various raw materials and natural sources. These APIs are then subjected to a series of purification, formulation, and quality control steps to ensure their safety, efficacy, and compliance with regulatory standards. Advanced technologies, such as continuous manufacturing, biotechnology, and nanotechnology, are increasingly being adopted to improve efficiency, reduce waste, and enhance the quality of pharmaceutical products.

Production inputs

The manufacture of basic pharmaceutical products requires a diverse range of inputs, including specialized raw materials, such as organic and inorganic chemicals, biological materials, and natural compounds. Additionally, this industry relies on sophisticated production equipment, including reactors, centrifuges, filtration systems, and packaging machinery. Skilled labor, including chemists, engineers, and quality control personnel, is also a critical input for this highly technical and regulated industry.

Production outputs

The primary outputs of the basic pharmaceutical products industry are the active pharmaceutical ingredients (APIs) and finished drug formulations that are used in a wide range of healthcare applications. These products are then consumed by other NACE codes, such as 21.20 Manufacture of pharmaceutical preparations, 86.10 Hospital activities, and 86.90 Other human health activities, which are responsible for the further processing, distribution, and administration of these essential medicines.

Revisions to 21.10

Classification codes are adjusted frequently. The code may have been revised or replaced between system versions. The table below shows the history (newest to oldest) of the code 21.10. The most recent 1 version of this code (21.10) is in the NACE v2.1 system:

This page shows a legacy version of code 21.10 ( NACE v2.0).

Newer versions

Related Tariff Codes (HS / Harmonized System)

These HS codes are related to this econ code: (21.10).

HS code HS year HS title
291821HS v2017Acids; carboxylic acids, (with phenol function but without other oxygen function), salicylic acid and its salts
291822HS v2017Acids; carboxylic acids, (with phenol function but without other oxygen function), o-acetylsalicylic acid, its salts and esters
291823HS v2017Acids; carboxylic acids, (with phenol function but without other oxygen function), other esters of salicylic acid and its salts n.e.c. in item no. 2918.2
292241HS v2017Amino-acids, other than those containing more than one kind of oxygen function, and their esters; lysine and its esters; salts thereof
292242HS v2017Amino-acids, other than those containing more than one kind of oxygen function, and their esters; glutamic acid and its esters; salts thereof
292310HS v2017Quaternary ammonium salts and hydroxides; choline and its salts, whether or not chemically defined
292320HS v2017Lecithins and other phosphoaminolipids, whether or not chemically defined
292330HS v2017Quaternary ammonium salts and hydroxides; tetraethylammonium perfluorooctane sulphonate, whether or not chemically defined
292340HS v2017Quaternary ammonium salts and hydroxides; didecyldimethylammonium perfluorooctane sulphonate, whether or not chemically defined
292390HS v2017Quaternary ammonium salts and hydroxides; whether or not chemically defined n.e.c. in heading no. 2923
292411HS v2017Acyclic amides (including acyclic carbamates) and their derivatives; salts thereof; meprobamate (INN)
292412HS v2017Acyclic amides (including acyclic carbamates) and their derivatives; salts thereof; fluoroacetamide (ISO), monocrotophos (ISO) and phosphamidon (ISO)
292419HS v2017Acyclic amides (including acyclic carbamates) and their derivatives; salts thereof, other than meprobamate (INN), fluoroacetamide (ISO), monocrotophos (ISO) or phosphamidon (ISO)
292423HS v2017Cyclic amides (including cyclic carbamates) and their derivatives; 2-acetamidobenzoic acid (N-acetylanthranillic acid) and its salts
292424HS v2017Cyclic amides (including cyclic carbamates) and their derivatives; ethinamate and its salts
292425HS v2017Cyclic amides (including cyclic carbamates) and their derivatives; alachlor (ISO) and its salts
292429HS v2017Cyclic amides (including cyclic carbamates) and their derivatives; other than the derivatives and salts of ureines, 2-acetamidobenzoic acid (N-acetylanthancillic acid),ethinamate S, and alachlor (ISO) and their derivatives and salts
293220HS v2017Heterocyclic compounds; with oxygen hetero-atom(s) only, containing an unfused furan ring (whether or not hydrogenated) in the structure, lactones
293311HS v2017Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused pyrazole ring (whether or not hydrogenated) in the structure, phenazone (antipyrin) and its derivatives
293319HS v2017Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused pyrazole ring (whether or not hydrogenated) in the structure, other than henazone (antipyrin) and its derivatives
293321HS v2017Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused imidazole ring (whether or not hydrogenated) in the structure, hydantoin and its derivatives
293352HS v2017Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, malonylurea (barbituric acid) and its salts
293353HS v2017Allobarbital (INN), amobarbital (INN), barbital (INN), butalbital (INN), butobarbital, cyclobarbital (INN), methylphenobarbital (INN), pentobarbital (INN), phenobarbital (INN), secbutabarbital (INN), secobarbital (INN) and vinylbital (INN); salts thereof
293354HS v2017Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, other derivatives of malonylurea (barbituric acid) and salts thereof, n.e.c. in 2933.53
293355HS v2017Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure; loprazolam (INN), mecloqualone (INN), methaqualone (INN), and zipeprol (INN); salts thereof
293359HS v2017Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, (other than malonylurea and its derivatives, loprazolam, mecloqualone, methaqualone, zipeprol, and salts thereof) n.e.c. in 2933.5
293369HS v2017Heterocyclic compounds; containing an unfused triazine ring (whether or not hydrogenated) in the structure, others excluding melamine
293430HS v2017Heterocyclic compounds; containing in the structure, a phenothiazine ring-system (whether or not hydrogenated), not further fused
293510HS v2017Sulphonamides; N-methylperfluorooctane sulphonamide
293520HS v2017Sulphonamides; N-ethylperfluorooctane sulphonamide
293530HS v2017Sulphonamides; N-ethyl-N-(2-hydroxyethyl) perfluorooctane sulphonamide
293540HS v2017Sulphonamides; N-(2-hydroxyethyl)-N-methylperfluorooctane sulphonamide
293550HS v2017Sulphonamides; other perfluorooctane sulphonamides
293590HS v2017Sulphonamides; n.e.c. in heading no. 2935
293980HS v2017Alkaloids; natural or reproduced by synthesis, and their salts, esters and other derivatives n.e.c. in heading no. 2939
294000HS v2017Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose; sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37, 29.38, or 29.39
293621HS v2017Vitamins; vitamins A and their derivatives, unmixed
293622HS v2017Vitamins; vitamin B1 and its derivatives, unmixed
293623HS v2017Vitamins; vitamin B2 and its derivatives, unmixed
293624HS v2017Vitamins; D- or DL-pantothenic acid (vitamin B3 or vitamin B5) and its derivatives, unmixed
293625HS v2017Vitamins; vitamin B6 and its derivatives, unmixed
293626HS v2017Vitamins; vitamin B12 and its derivatives, unmixed
293627HS v2017Vitamins; vitamin C and its derivatives, unmixed
293628HS v2017Vitamins; vitamin E and its derivatives, unmixed
293629HS v2017Vitamins; n.e.c. in item no. 2936.2, and their derivatives, unmixed
293690HS v2017Vitamins; n.e.c. in heading no. 2936, including natural concentrates
293711HS v2017Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives and structural analogues; somatotropin, its derivatives and structural analogues
293712HS v2017Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives and structural analogues; insulin and its salts
293719HS v2017Polypeptide hormones, protein hormones and glycoprotein hormones, their derivatives and structural analogues; other than somatotropin, (its derivatives and structural anaologues) and insulin and its salts
293721HS v2017Steroidal hormones, their derivatives and structural analogues; cortisone, hydrocortisone, prednisone (dehydrocortisone) and prednisolone (dehydrohydrocortisone)
293722HS v2017Steroidal hormones, their derivatives and structural analogues; halogenated derivatives of corticosteroidal hormones
293723HS v2017Steroidal hormones, their derivatives and structural analogues; oestrogens and progestogens
293729HS v2017Steroidal hormones, their derivatives and structural analogues; other than cortisone, hydrocortisone, prednisone (dehydrocortisone), prednisolone (dehydrohydrocortisone), halogenated derivatives of corticosteroidal hormones, oestrogen and progestogens
293750HS v2017Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues
293790HS v2017Hormones, prostaglandins, thromboxanes and leukotrienes, natural or reproduced by synthesis; derivatives and structural analogues thereof, including chain modified polypeptides, used primarily as hormones, n.e.c. in heading 2937
293810HS v2017Glycosides; rutoside (rutin) and its derivatives
293890HS v2017Glycosides; natural or reproduced by synthesis, other than rutoside (rutin) and its derivatives
293911HS v2017Alkaloids; of opium and their derivatives; salts thereof
293919HS v2017Alkaloids; of opium and their derivatives; other than in 2939.11, salts thereof
293920HS v2017Alkaloids; of cinchona and their derivatives; salts thereof
293930HS v2017Alkaloids; caffeine and its salts
293941HS v2017Alkaloids; ephedrine and its salts
293942HS v2017Alkaloids; pseudoephedrine (INN) and its salts
293943HS v2017Alkaloids; cathine (INN) and its salts
293944HS v2017Alkaloids; norephedrine and its salts
293949HS v2017Alkaloids; other than ephedrine, pseudoephedrine (INN), norephedrine, and cathine (INN) and their salts
293951HS v2017Alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, fenetylline (INN) and its salts
293959HS v2017Alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, other than fenetylline
293961HS v2017Alkaloids; of rye ergot and their derivatives, ergometrine (INN) and its salts
293962HS v2017Alkaloids; of rye ergot and their derivatives, ergotamine (INN) and its salts
293963HS v2017Alkaloids; of rye ergot and their derivatives, lysergic acid and its salts
293969HS v2017Alkaloids; of rye ergot and their derivatives, salts thereof, n.e.c. in item no. 2939.6
293971HS v2017Alkaloids; of vegetal origin, cocaine, ecgonine, levometamfetamine, metamfetamine (INN), metamfetamine racemate; salts, esters and other derivatives thereof
293979HS v2017Alkaloids; of vegetal origin, other than cocaine, ecgonine, levometamfetamine, metamfetamine (INN), metamfetamine racemate; salts, esters and other derivatives; n.e.c. in heading no. 2939
294110HS v2017Antibiotics; penicillins and their derivatives with a penicillanic acid structure; salts thereof
294120HS v2017Antibiotics; streptomycins and their derivatives; salts thereof
294130HS v2017Antibiotics; tetracyclines and their derivatives; salts thereof
294140HS v2017Antibiotics; chloramphenicol and its derivatives; salts thereof
294150HS v2017Antibiotics; erythromycin and its derivatives; salts thereof
294190HS v2017Antibiotics; n.e.c. in heading no. 2941
300310HS v2017Medicaments; containing penicillins, streptomycins or their derivatives, for therapeutic or prophylactic uses, (not in measured doses, not packaged for retail sale)
300320HS v2017Medicaments; containing antibiotics other than penicillins, streptomycins and their derivatives, for therapeutic or prophylactic uses, (not in measured doses, not packaged for retail sale)
300331HS v2017Medicaments; containing insulin, for therapeutic or prophylactic uses, not packaged for retail sale
300339HS v2017Medicaments; containing hormones (excluding insulin), (but not containing antibiotics), for therapeutic or prophylactic uses, not packaged for retail sale
300341HS v2017Medicaments; containing alkaloids or their derivatives, containing ephedrine or its salts, for therapeutic or prophylactic uses, (not packaged for retail sale)
300342HS v2017Medicaments; containing alkaloids or their derivatives, containing pseudoephedrine (INN) or its salts, for therapeutic or prophylactic uses, (not packaged for retail sale)
300343HS v2017Medicaments; containing alkaloids or their derivatives, containing norephedrine or its salts, for therapeutic or prophylactic uses, (not packaged for retail sale)
300349HS v2017Medicaments; containing alkaloids or their derivatives; other than ephedrine, pseudoephedrine (INN) or norephedrine or their salts; for therapeutic or prophylactic uses, (not packaged for retail sale)
300360HS v2017Medicaments; containing antimalarial active principles described in subheading note 2 to this chapter, for therapeutic or prophylactic uses, (not packaged for retail sale)
300390HS v2017Medicaments; (not containing antibiotics, hormones, alkaloids or their derivatives), for therapeutic or prophylactic uses, (not packaged for retail sale)
300410HS v2017Medicaments; containing penicillins, streptomycins or their derivatives, for therapeutic or prophylactic uses, packaged for retail sale
300420HS v2017Medicaments; containing antibiotics (other than penicillins, streptomycins or their derivatives), for therapeutic or prophylactic uses, packaged for retail sale
300431HS v2017Medicaments; containing insulin, for therapeutic or prophylactic uses, packaged for retail sale
300432HS v2017Medicaments; containing corticosteroid hormones, their derivatives or structural analogues (but not containing antibiotics), for therapeutic or prophylactic uses, packaged for retail sale
300439HS v2017Medicaments; containing hormones (but not insulin), adrenal cortex hormones or antibiotics, for therapeutic or prophylactic uses, packaged for retail sale
300441HS v2017Medicaments; containing alkaloids or their derivatives, containing ephedrine or its salts, for therapeutic or prophylactic uses, packaged for retail sale
300442HS v2017Medicaments; containing alkaloids or their derivatives, containing pseudoephedrine (INN) or its salts, for therapeutic or prophylactic uses, packaged for retail sale
300443HS v2017Medicaments; containing alkaloids or their derivatives, containing norephedrine or its salts, for therapeutic or prophylactic uses, packaged for retail sale
300449HS v2017Medicaments; containing alkaloids or their derivatives; other than ephedrine, pseudoephedrine (INN) or norephedrine or their salts; for therapeutic or prophylactic uses, packaged for retail sale
300450HS v2017Medicaments; containing vitamins or their derivatives, for therapeutic or prophylactic use, packaged for retail sale
300460HS v2017Medicaments; containing antimalarial active principles described in Subheading Note 2 to this Chapter, for therapeutic or prophylactic uses, packaged for retail sale
300490HS v2017Medicaments; consisting of mixed or unmixed products n.e.c. in heading no. 3004, for therapeutic or prophylactic uses, packaged for retail sale
300120HS v2017Glands and other organs; extracts of glands or other organs or of their secretions, for organo-therapeutic uses
300190HS v2017Glands and other organs; heparin and its salts; other human or animal substances prepared for therapeutic or prophylactic uses, n.e.c. in heading 3001
300211HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; malaria diagnostic test kits
300212HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; antisera and other blood fractions
300213HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; immunological products, unmixed, not put up in measured doses or in forms or packings for retail sale
300214HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; immunological products, mixed, put up in measured doses or in forms or packings for retail sale
300215HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; immunological products, put up in measured doses or in forms or packings for retail sale
300219HS v2017Blood, human or animal, antisera, other blood fractions and immunological products; n.e.c. in heading 3002.1
300220HS v2017Vaccines; for human medicine
300230HS v2017Vaccines; for veterinary medicine
300290HS v2017Toxins, cultures of micro-organisms (excluding yeasts) and similar products
300510HS v2017Dressings, adhesive; and other articles having an adhesive layer, packed for retail sale for medical, surgical, dental or veterinary purposes
300590HS v2017Wadding, gauze, bandages and similar articles; (excluding adhesive dressings), impregnated or coated with pharmaceutical substances, packaged for retail sale
300620HS v2017Pharmaceutical goods; blood-grouping reagents
300630HS v2017Pharmaceutical goods; opacifying preparations for x-ray examinations, diagnostic reagents designed to be administered to the patient
300660HS v2017Pharmaceutical goods; chemical contraceptive preparations based on hormones, on other products of heading 2937 or on spermicides

Related ISIC Codes

These isic codes are related to this econ code: (21.10).

ISIC code ISIC Version ISIC title
2100ISIC v4.0Manufacture of pharmaceuticals, medicinal chemical and botanical products

Related CPC Codes

These CPC codes are related to this econ code: (21.10).

CPC code CPC Version CPC title
35210CPC v2.1Salicylic acid and its salts and esters
35220CPC v2.1Lysine and its esters and salts thereof; glutamic acid and its salts; quaternary ammonium salts and hydroxides; lecithins and other phosphoaminolipids; acyclic amides and their derivatives and salts thereof; cyclic amides (except ureines) and their derivatives and salts
35230CPC v2.1Lactones n.e.c., heterocyclic compounds with nitrogen hetero-atom(s) only, containing an unfused pyrazole ring, a pyrimidine ring, a piperazine ring, an unfused triazine ring or a phenothiazine ring system not further fused; hydantoin and its derivatives; sulphonamides
35240CPC v2.1Sugars, chemically pure n.e.c.; sugar ethers and sugar esters and their salts n.e.c.
35250CPC v2.1Provitamins, vitamins and hormones; glycosides and vegetable alkaloids and their salts, ethers, esters and other derivatives; antibiotics
35260CPC v2.1Medicaments, for therapeutic or prophylactic uses
35270CPC v2.1Other pharmaceutical products
88430CPC v2.1Pharmaceutical product manufacturing services

Family tree for manufacture of basic pharmaceutical products

    graph LR
    A["<a href='/classifications/nace/v2/C'>C: MANUFACTURING</a>"]
A --> B["<a href='/classifications/nace/v2/C/21'>21: Manufacture of basic pharmaceutical products and pharmaceutical preparations</a>"]
B --> C["<a href='/classifications/nace/v2/C/21/1'>21.1: Manufacture of basic pharmaceutical products</a>"]
C --> D["<a href='/classifications/nace/v2/C/21/10'>21.10: Manufacture of basic pharmaceutical products</a>"]

    
    

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