Alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, other than fenetylline

HS v2022 Code: 293959

About alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, other than fenetylline

HS code 293959 covers a range of alkaloid compounds, including theophylline and aminophylline, which are widely used in the pharmaceutical industry. These substances play a crucial role in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). The global demand for these alkaloids continues to grow, driven by the increasing prevalence of respiratory illnesses and the ongoing development of new therapeutic applications.

Production process

The production of the alkaloids covered under HS code 293959 typically involves a multi-step chemical synthesis process. This often begins with the extraction of the raw materials, such as plant-based sources, followed by a series of purification, separation, and derivatization steps to obtain the desired compounds. Advanced techniques like chromatography, crystallization, and recrystallization are commonly employed to ensure the purity and quality of the final products.

Production inputs

The main inputs required for the production of the alkaloids under HS code 293959 include various plant-based raw materials, such as tea leaves, cocoa beans, and kola nuts, which serve as the primary sources of the alkaloid compounds. Additionally, the industry relies on a range of chemical reagents, solvents, and specialized equipment, such as reactors, distillation columns, and purification systems, to facilitate the complex synthesis and extraction processes.

Production outputs

The alkaloids produced under HS code 293959 are primarily used as active pharmaceutical ingredients (APIs) in the manufacture of various respiratory medications, including bronchodilators, anti-asthmatic drugs, and methylxanthine-based therapies. These alkaloids may also find applications in the production of 293999 (Other heterocyclic compounds with nitrogen hetero-atom(s) only), as well as in the formulation of dietary supplements and energy drinks.

Revisions to 293959

Classification codes are adjusted frequently. The code may have been revised or replaced between system versions. The table below shows the history (newest to oldest) of the code 293959. The most recent 1 version of this code (293959) is in the HS v2022 system (this version):

This page shows the most recent version of code 293959.

Family tree for alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, other than fenetylline

    graph LR
    A["<a href='/classifications/hs/v2022/29'>29: Organic chemicals</a>"]
A --> B["<a href='/classifications/hs/v2022/2939'>2939: Alkaloids; natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives</a>"]
B --> C["<a href='/classifications/hs/v2022/293959'>293959: Alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, other than fenetylline</a>"]

    B --> D["<a href='/classifications/hs/v2022/293911'>293911: Alkaloids; of opium and their derivatives; salts thereof</a>"]
B --> E["<a href='/classifications/hs/v2022/293919'>293919: Alkaloids; of opium and their derivatives; other than in 2939.11, salts thereof</a>"]
B --> F["<a href='/classifications/hs/v2022/293920'>293920: Alkaloids; of cinchona and their derivatives; salts thereof</a>"]
B --> G["<a href='/classifications/hs/v2022/293930'>293930: Alkaloids; caffeine and its salts</a>"]
B --> H["<a href='/classifications/hs/v2022/293941'>293941: Alkaloids; of ephedrine and their derivatives; salts thereof</a>"]
B --> I["<a href='/classifications/hs/v2022/293942'>293942: Alkaloids; of ephedrine and their derivatives; pseudoephedrine (INN) and its salts</a>"]
B --> J["<a href='/classifications/hs/v2022/293943'>293943: Alkaloids; of ephedrine and their derivatives; cathine (INN) and its salts</a>"]
B --> K["<a href='/classifications/hs/v2022/293944'>293944: Alkaloids; of ephedrine and their derivatives; norephedrine and its salts</a>"]
B --> L["<a href='/classifications/hs/v2022/293945'>293945: Alkaloids; of ephedrine and their derivatives; levometamfetamine, metamfetamine (INN), metamefetamine racemate and their salts</a>"]
B --> M["<a href='/classifications/hs/v2022/293949'>293949: Alkaloids; of ephedrine and their derivatives; other than ephedrine, pseudoephedrine (INN), norephedrine, cathine (INN), levometamfetamine, metamfetamine (INN), metamefetamine racemate and their salts</a>"]
B --> N["<a href='/classifications/hs/v2022/293951'>293951: Alkaloids; theophylline and aminophylline (theophylline-ethylenediamine) and their derivatives; salts thereof, fenetylline (INN) and its salts</a>"]
B --> O["<a href='/classifications/hs/v2022/293961'>293961: Alkaloids; of rye ergot and their derivatives, ergometrine (INN) and its salts</a>"]
B --> P["<a href='/classifications/hs/v2022/293962'>293962: Alkaloids; of rye ergot and their derivatives, ergotamine (INN) and its salts</a>"]
B --> Q["<a href='/classifications/hs/v2022/293963'>293963: Alkaloids; of rye ergot and their derivatives, lysergic acid and its salts</a>"]
B --> R["<a href='/classifications/hs/v2022/293969'>293969: Alkaloids; of rye ergot and their derivatives, salts thereof, n.e.c. in item no. 2939.6</a>"]
B --> S["<a href='/classifications/hs/v2022/293972'>293972: Alkaloids; of vegetal origin, cocaine, ecgonine; salts, esters and other derivatives thereof</a>"]
B --> T["<a href='/classifications/hs/v2022/293979'>293979: Alkaloids; of vegetal origin, other than cocaine, ecgonine; salts, esters and other derivatives; n.e.c. in heading no. 2939</a>"]
B --> U["<a href='/classifications/hs/v2022/293980'>293980: Alkaloids; natural or reproduced by synthesis, and their salts, esters and other derivatives n.e.c. in heading no. 2939</a>"]

    

    %% Color coordination by level

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    classDef level2 color:#000,fill:#e0a458,stroke:#333,stroke-width:1px
    classDef level3 color:#000,fill:#419d78,stroke:#333,stroke-width:1px
    classDef level4 color:#000,fill:#c04abc,stroke:#333,stroke-width:1px
    classDef level5 color:#000,fill:#f1c40f,stroke:#333,stroke-width:1px
    classDef level6 color:#000,fill:#f1c40f,stroke:#333,stroke-width:1px
    classDef highlight color:#000,fill:#fff,stroke:#000,stroke-width:5px



  %% Apply classes
  class A level2
class B level4
class C level6
class D level6
class E level6
class F level6
class G level6
class H level6
class I level6
class J level6
class K level6
class L level6
class M level6
class N level6
class O level6
class P level6
class Q level6
class R level6
class S level6
class T level6
class U level6

  class C highlight

  %% class A level1
  %% class B,C level2
  %% class D,E,F,G,H,I level2
  %% class J,K,L,M,N,O,P level3
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