Heterocyclic compounds; alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN), clorazepate, delorazepam (INN), diazepam (INN), estazolam (INN), ethyl loflazepate (INN), fludiazepam (INN), flunitrazepam (INN), (cont)

HS v2022 Code: 293391

About heterocyclic compounds; alprazolam (inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate, delorazepam (inn), diazepam (inn), estazolam (inn), ethyl loflazepate (inn), fludiazepam (inn), flunitrazepam (inn), (cont)

HS code 293391 covers a range of heterocyclic compounds, primarily benzodiazepines, which are widely used in the pharmaceutical industry. These compounds play a crucial role in the production of various medications, including anxiolytics, sedatives, and anticonvulsants. The global demand for these substances continues to grow, driven by the increasing prevalence of mental health conditions and the need for effective therapeutic options.

Production process

The production of the compounds covered under HS code 293391 typically involves complex organic synthesis processes. Key steps may include ring formation, halogenation, and various functional group manipulations. Manufacturers often utilize advanced techniques such as catalytic reactions, cryogenic conditions, and purification methods to ensure the high purity and quality of the final products.

Production inputs

The main inputs required for the production of HS code 293391 compounds include a range of organic chemicals, such as benzene derivatives, halogenated compounds, and various reagents. Specialized equipment, such as chemical reactors, distillation columns, and analytical instruments, are also essential for the manufacturing process. Additionally, skilled personnel with expertise in organic chemistry and pharmaceutical production are crucial for the successful development and commercialization of these heterocyclic compounds.

Production outputs

The compounds covered under HS code 293391 are primarily used as active pharmaceutical ingredients (APIs) in the production of various medications. These APIs are then further processed and formulated by the 300000 Pharmaceutical Preparations industry, which produces the final drug products for distribution and consumption. The outputs of HS code 293391 also serve as key intermediates for the synthesis of other 293000 Organic Chemicals used in the broader chemical industry.

Revisions to 293391

Classification codes are adjusted frequently. The code may have been revised or replaced between system versions. The table below shows the history (newest to oldest) of the code 293391. The most recent 1 version of this code (293391) is in the HS v2022 system (this version):

This page shows the most recent version of code 293391.

Family tree for heterocyclic compounds; alprazolam (inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate, delorazepam (inn), diazepam (inn), estazolam (inn), ethyl loflazepate (inn), fludiazepam (inn), flunitrazepam (inn), (cont)

    graph LR
    A["<a href='/classifications/hs/v2022/29'>29: Organic chemicals</a>"]
A --> B["<a href='/classifications/hs/v2022/2933'>2933: Heterocyclic compounds with nitrogen hetero-atom(s) only</a>"]
B --> C["<a href='/classifications/hs/v2022/293391'>293391: Heterocyclic compounds; alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN), clorazepate, delorazepam (INN), diazepam (INN), estazolam (INN), ethyl loflazepate (INN), fludiazepam (INN), flunitrazepam (INN), (cont)</a>"]

    B --> D["<a href='/classifications/hs/v2022/293311'>293311: Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused pyrazole ring (whether or not hydrogenated) in the structure, phenazone (antipyrin) and its derivatives</a>"]
B --> E["<a href='/classifications/hs/v2022/293319'>293319: Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused pyrazole ring (whether or not hydrogenated) in the structure, other than henazone (antipyrin) and its derivatives</a>"]
B --> F["<a href='/classifications/hs/v2022/293321'>293321: Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused imidazole ring (whether or not hydrogenated) in the structure, hydantoin and its derivatives</a>"]
B --> G["<a href='/classifications/hs/v2022/293329'>293329: Heterocyclic compounds; with nitrogen hetero-atom(s) only, containing an unfused imidazole ring (whether or not hydrogenated) in the structure, other than hydantoin and its derivatives</a>"]
B --> H["<a href='/classifications/hs/v2022/293331'>293331: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, pyridine and its salts</a>"]
B --> I["<a href='/classifications/hs/v2022/293332'>293332: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, piperidine and its salts</a>"]
B --> J["<a href='/classifications/hs/v2022/293333'>293333: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, alfentanil (INN), anileridine (INN), bezitramide (INN), bromazepam (INN), carfentanil (INN), difenoxin (INN), diphenoxylate (INN), dipipanone (INN)</a>"]
B --> K["<a href='/classifications/hs/v2022/293334'>293334: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, other fentanyls and their derivatives</a>"]
B --> L["<a href='/classifications/hs/v2022/293335'>293335: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, 3-quinuclidinol</a>"]
B --> M["<a href='/classifications/hs/v2022/293336'>293336: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, 4-anilino-N-phenethylpiperidine (ANPP)</a>"]
B --> N["<a href='/classifications/hs/v2022/293337'>293337: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, N-phenethyl-4-piperdone (NPP)</a>"]
B --> O["<a href='/classifications/hs/v2022/293339'>293339: Heterocyclic compounds; containing an unfused pyridine ring (whether or not hydrogenated) in the structure, n.e.c. in 2933.3</a>"]
B --> P["<a href='/classifications/hs/v2022/293341'>293341: Heterocyclic compounds; containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) in the structure, not further fused, levorphanol (INN) and its salts</a>"]
B --> Q["<a href='/classifications/hs/v2022/293349'>293349: Heterocyclic compounds; containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) in the structure, not further fused, other than levorphanol (INN) and its salts</a>"]
B --> R["<a href='/classifications/hs/v2022/293352'>293352: Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, malonylurea (barbituric acid) and its salts</a>"]
B --> S["<a href='/classifications/hs/v2022/293353'>293353: Allobarbital (INN), amobarbital (INN), barbital (INN), butalbital (INN), butobarbital, cyclobarbital (INN), methylphenobarbital (INN), pentobarbital (INN), phenobarbital (INN), secbutabarbital (INN), secobarbital (INN) and vinylbital (INN); salts thereof</a>"]
B --> T["<a href='/classifications/hs/v2022/293354'>293354: Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, other derivatives of malonylurea (barbituric acid) and salts thereof, n.e.c. in 2933.53</a>"]
B --> U["<a href='/classifications/hs/v2022/293355'>293355: Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure; loprazolam (INN), mecloqualone (INN), methaqualone (INN), and zipeprol (INN); salts thereof</a>"]
B --> V["<a href='/classifications/hs/v2022/293359'>293359: Heterocyclic compounds; containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, (other than malonylurea and its derivatives, loprazolam, mecloqualone, methaqualone, zipeprol, and salts thereof) n.e.c. in 2933.5</a>"]
B --> W["<a href='/classifications/hs/v2022/293361'>293361: Heterocyclic compounds; containing an unfused triazine ring (whether or not hydrogenated) in the structure, melamine</a>"]
B --> X["<a href='/classifications/hs/v2022/293369'>293369: Heterocyclic compounds; containing an unfused triazine ring (whether or not hydrogenated) in the structure, others excluding melamine</a>"]
B --> Y["<a href='/classifications/hs/v2022/293371'>293371: Heterocyclic compounds; lactams; 6-hexanelactam (epsilon-caprolactam)</a>"]
B --> Z["<a href='/classifications/hs/v2022/293372'>293372: Heterocyclic compounds; lactams; clobazam (INN) and methyprylon (INN)</a>"]
B --> BA["<a href='/classifications/hs/v2022/293379'>293379: Heterocyclic compounds; lactams; other than 6-hexanelactam (epsilon caprolactam) and clobazam (INN) and methyprylon (INN)</a>"]
B --> BB["<a href='/classifications/hs/v2022/293392'>293392: Heterocyclic compounds; azinphos-methyl (ISO)</a>"]
B --> BC["<a href='/classifications/hs/v2022/293399'>293399: Heterocyclic compounds; n.e.c. in headings no. 2933</a>"]

    

    %% Color coordination by level

    classDef level1 color:#000,fill:#a8f9ff,stroke:#333,stroke-width:2px
    classDef level2 color:#000,fill:#e0a458,stroke:#333,stroke-width:1px
    classDef level3 color:#000,fill:#419d78,stroke:#333,stroke-width:1px
    classDef level4 color:#000,fill:#c04abc,stroke:#333,stroke-width:1px
    classDef level5 color:#000,fill:#f1c40f,stroke:#333,stroke-width:1px
    classDef level6 color:#000,fill:#f1c40f,stroke:#333,stroke-width:1px
    classDef highlight color:#000,fill:#fff,stroke:#000,stroke-width:5px



  %% Apply classes
  class A level2
class B level4
class C level6
class D level6
class E level6
class F level6
class G level6
class H level6
class I level6
class J level6
class K level6
class L level6
class M level6
class N level6
class O level6
class P level6
class Q level6
class R level6
class S level6
class T level6
class U level6
class V level6
class W level6
class X level6
class Y level6
class Z level6
class BA level6
class BB level6
class BC level6

  class C highlight

  %% class A level1
  %% class B,C level2
  %% class D,E,F,G,H,I level2
  %% class J,K,L,M,N,O,P level3
  %% class C highlight